The Back Bay neighborhood of Boston is probably best known for its ample high-end shopping boutiques, but it also features some excellent architecture (the Boston Public Library being a great example), and a good bar and restaurant scene. The neighborhood is in close proximity to other prominent areas of Boston you will likely want to visit during your Boston stay, making it a great lodging option. The Back Bay Hotel, once the headquarters of the Boston Police, is a really great choice if you are looking for a mid-to-high-end Hotel with a lot of old-school Beantown character. The Copley Square Hotel, the Westin Copley Place, and the Newbury Guesthouse are other great similarly priced hotels in the area, while the Mandarin Oriental Boston is the top-of-the-line if you are looking to really splurge on your Boston accommodations.
Downtown Boston is home to some of the best hotels in the city, and features attractions such as Boston Common (the oldest park in the US), the Boston Massacre Monument, and many other prominent sites of American historical note. Downtown is very close to other popular Boston neighborhoods, making it an excellent centrally located place to stay in the city. Great lodging options Downtown include Club Quarters, Harborside Inn of Boston, and ultra-cool boutique hotel Ames, one of the trendiest and hippest places to stay in all of Boston.
The North end of Boston is known for its boutique shops and relevant historical sights (including the house of the legendary Paul Revere), its cobblestone streets reminiscent of old Boston, and the prominent Italian influence on its culture. A hipster youth element is also emerging in the area, making it one of the cooler neighborhoods in the city for bars and nightlife. The Harborside Inn of Boston is a great budget lodging choice in the area, while the Boston Harbor Hotel is an unbeatable five-star offering. For mid-priced accommodations, you might look at the waterside Fairmont Battery Wharf Boston.
The neighboring Financial District/Waterfront neighborhoods of Boston feature attractions such as the Boston Harbor Walk and the New England Aquarium. The area features easy access to the Boston Logan International Airport, making it a convenient place to stay for air travelers. You will also find a solid nightlife and some great dining options in the area. If you want to stay in the vicinity of the Financial District/Waterfront areas of Boston, consider hotels such as the Millennium Bostonian Hotel, and the Hilton Boston Downtown/Financial District.
Cambridge is clearly famous for its educational institutions as home to both Harvard and MIT, but it is also known as one of the more eclectic cultural hubs in greater Boston. If you are looking for a wide variety of ethnic dining options, Cambridge may be the best place to be in the Boston Metro area. As a center of intellectual thought, Cambridge has a thriving bookstore and coffeehouse culture, and a lot of interesting independent shops. It is also home to an excellent nightlife, due in part to the major colleges that form the basis of Cambridge culture. The Whitman House, the Harding House, and Le Meridian Cambridge-MIT are excellent mid-priced lodging options in Cambridge.
The Fenway/Kenmore section of Boston not only includes the world-famous Fenway Park, but is also home to a booming bar and restaurant scene and a lot of interesting shops. If catching a Red Sox game is at the center of your Boston travel itinerary you might want to stay in the vicinity of the ballpark. The Hotel Commonwealth is a popular Boston boutique hotel that may be your best option if visiting Boston for a Sox game; some rooms even face Fenway Park, sure to please any die-hard baseball enthusiast.